Bible Verses About Depression: 15 Helpful Scriptures

by Pamela Rose Williams · Print Print · Email Email

Depression is something that has been around for thousands of years. WebMD uses the following words in its definition of depression “Major depression is an episode of sadness or apathy along with other symptoms that lasts at least two consecutive weeks and is severe enough to interrupt daily activities” [1]. People who suffer from depression often are sad or uninterested in anything. Depressed people sleep a lot and enjoy spending time in darkness, rather than the light. God’s Word encourages us to come out of the darkness and concentrate on the things of others.  This will take our focus off of ourselves and help us to find true peace and joy in serving others. I have found some things in the Bible that should help you to overcome depressing times.  Take a look at these 15 helpful Scriptures.

Featured Memory Verse:  Philippians 4:8 Finally, brothers, whatever is true, whatever is honorable, whatever is just, whatever is pure, whatever is lovely, whatever is commendable, if there is any excellence, if there is anything worthy of praise, think about these things.

God Never Loses Sight of You 

Deuteronomy 31:8 “… It is the LORD who goes before you. He will be with you; he will not leave you or forsake you. Do not fear or be dismayed.”

In a desert land he found him, in a barren and howling waste.

Deuteronomy 32:10In a desert land he found him, in a barren and howling waste. He shielded him and cared for him; he guarded him as the apple of his eye. 

Psalms 34:17 When the righteous cry for help, the LORD hears and delivers them out of all their troubles.

Psalms 40:1-3 I waited patiently for the LORD; he inclined to me and heard my cry. He drew me up from the pit of destruction, out of the miry bog, and set my feet upon a rock, making my steps secure. He put a new song in my mouth, a song of praise to our God. Many will see and fear, and put their trust in the LORD.

Your Trust and Hope is In Him; Call Upon Him 

Psalms 3:3 But you, O LORD, are a shield about me, my glory, and the lifter of my head.

Psalms 32:10 Many are the sorrows of the wicked, but steadfast love surrounds the one who trusts in the LORD.

Psalms 37:3-4 Trust in the LORD, and do good; dwell in the land and befriend faithfulness. Delight yourself in the LORD, and he will give you the desires of your heart. 

Psalms 42:11 Why are you cast down, O my soul, and why are you in turmoil within me? Hope in God; for I shall again praise him, my salvation and my God.

1 Peter 5:6-7 (KJV) Humble yourselves therefore under the mighty hand of God, that he may exalt you in due time: Casting all your care upon him; for he careth for you.

He Has Great Plans for You; Hang in There 

Jeremiah 29:11 For I know the plans I have for you, declares the LORD, plans for welfare and not for evil, to give you a future and a hope.

John 16:33 I have said these things to you, that in me you may have peace. In the world you will have tribulation. But take heart; I have overcome the world. 

Romans 8:38-39 For I am sure that neither death nor life, nor angels nor rulers, nor things present nor things to come, nor powers, nor height nor depth, nor anything else in all creation, will be able to separate us from the love of God in Christ Jesus our Lord.

2 Corinthians 1:3-4 Blessed be the God and Father of our Lord Jesus Christ, the Father of mercies and God of all comfort, who comforts us in all our affliction, so that we may be able to comfort those who are in any affliction, with the comfort with which we ourselves are comforted by God.

1 Peter 4:12-13 Beloved, do not be surprised at the fiery trial when it comes upon you to test you, as though something strange were happening to you. But rejoice insofar as you share Christ’s sufferings, that you may also rejoice and be glad when his glory is revealed.

What Should I Do When I Fall Apart?

Be sure to listen to the video in the upper right of this page.  “Fall Apart” is a great song to help us realize that we need to call upon the Lord not only in the bad times — remember to count your blessings and praise Him for them too.


The Holy Bible, King James Version

The Holy Bible, English Standard Version

“Scripture quotations are from The Holy Bible, English Standard Version® (ESV®), copyright © 2001 by Crossway, a publishing ministry of Good News Publishers. Used by permission. All rights reserved.”

[1] WebMD www

YouTube “Fall Apart” by Josh Wilson

Photo by Hollie Williams

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{ 284 comments… read them below or add one }

mary October 21, 2014 at 4:33 pm

Please help me overcome depression and be happy again


Jack Wellman October 21, 2014 at 5:35 pm

I cannot help you overcome depression. Only God can but a great way to do this is to get your eyes off of yourself and start helping others by visiting the sick, visiting nursing home residents, witnessing to others about Christ and I would also talk to your pastor, stay in the Word at least every morning and evening and continue steadfast in prayer. I would even fast (if you have no medical problems such as diabetes). We have an article that addresses this very issue at this link Mary at: Don’t live this alone. Find fellow believers to pray with you, study with you, serve them, help the homeless in a soup kitchen.


Jayson September 21, 2015 at 8:02 pm

@Mary it also been a year now. I hope you have already overcome your depression. Always talk to God and know His reason for your troubles and heartache. Talk to your friends also it may help you.
Always trust God in everything! God bless!


bigscott January 31, 2015 at 7:24 pm

I need Gods love and support from this horrible depression, I am medicated but that can only do so much. I confess to my Lord my God that I am a horrible sinner of the mind. I need his strength and healing for that as well.
I confess the Lord Jesus Christ, is my Lord and Savior. Who died on the cross to give me eternal life and forgiveness of my sins. I repent and bow to my lord, spiritually and Physically. Please heal me of my mental illnesses and spiritual illnesses oh Lord!!!!!!!!!!!


Aaron February 18, 2015 at 8:33 am

I’m going through some depression right now myself. I’m a Christian… but I still get depressed at times. I’ve discovered for my situation the devil has been lying to me. Telling me how worthless I am… My depression is brought on my a string of situations where I seem to fail miserably… it lowers how i feel about myself (my self-worth).

I’ve found part of the key is you start meditating on scripture that will lift you up and see yourself how God sees you. It really has helped lift my spirits and change my focus… So be encouraged… there are a lot of encouraging scripture to help with depression. Also some that tells you how God sees how (which is different to how the devil sees you)

Some that have helped me:

Romans 8:38-39

Romans 8:1

Philippians 4:7

Philippians 4:8

Philippians 4:19

Psalm 40:1-3


brij April 29, 2015 at 3:37 am

Dont forget to nourish your physical body as well with good foods and remember your B vitamins are called your happiness vitamins, especially Niacin or B3.


MARY SANDERS June 28, 2015 at 2:17 am



Pamela Rose Williams June 28, 2015 at 10:43 am

Hi Mary, Here are some KJV verses for you to read and share with your friend:

Isaiah 41:10 – Fear thou not; for I [am] with thee: be not dismayed; for I [am] thy God: I will strengthen thee; yea, I will help thee; yea, I will uphold thee with the right hand of my righteousness.

1 Peter 5:7 – Casting all your care upon him; for he careth for you.

Joshua 1:5 – There shall not any man be able to stand before thee all the days of thy life: as I was with Moses, [so] I will be with thee: I will not fail thee, nor forsake thee.

Psalms 23:4 – Yea, though I walk through the valley of the shadow of death, I will fear no evil: for thou [art] with me; thy rod and thy staff they comfort me.

Deuteronomy 31:6 – Be strong and of a good courage, fear not, nor be afraid of them: for the LORD thy God, he [it is] that doth go with thee; he will not fail thee, nor forsake thee.

And this is always my favorite because when we think on the right things we cannot think on the things that make us lonely:

Philippians Chapter 4
6 Be careful for nothing; but in every thing by prayer and supplication with thanksgiving let your requests be made known unto God.
7 And the peace of God, which passeth all understanding, shall keep your hearts and minds through Christ Jesus.
8 Finally, brethren, whatsoever things are true, whatsoever things [are] honest, whatsoever things [are] just, whatsoever things [are] pure, whatsoever things [are] lovely, whatsoever things [are] of good report; if [there be] any virtue, and if [there be] any praise, think on these things.
9 Those things, which ye have both learned, and received, and heard, and seen in me, do: and the God of peace shall be with you.


Dwanna Benford July 4, 2015 at 9:03 pm

I really appreciated reading all of these scriptures to help me with the depression I am presently going through. I am truly blessed and am constantly praising God for the many positive happenings in my life. Last week my oldest son graduated high school and a couple weeks before God Blessed me with a full-time position at my job. I am so down because I really thought God sent me this guy I ended up dating for six months up until a month ago. I would see him everyday up until the evening I found him cheating on me at his apartment. I never seen any signs, he really acted like he cared for me. Even though it has been over a month now. I feel betrayed and worthless. I’m praying that God will give me strength to move on. Thanks and be blessed!


Pamela Rose Williams July 6, 2015 at 2:52 pm

Oh Dwanna, I am so sorry for the betrayal that you are feeling even now. I will pray along with you that you will received the peace from this situation that only our Heavenly Father can give to you.


dee August 28, 2015 at 11:00 am

ex preacher husband of 35 years ended marriage with internet sex and devasted.much prayer needed..


Jack Wellman August 28, 2015 at 4:28 pm

Hello Dee. I am so very sorry. Count on my prayer my friend in Christ.


Christina September 1, 2015 at 5:29 am

Dee, your husband’s behavior is a reflection of him and not you. I’ve said a prayer for you. A prayer of strength through this hardship, healing from a broken heart, peace for shaken soul, a renewal of your spirit, and the energy and desire to stand. God is with you. He has always been with you. He will lead you to the right people to assist you. He will lead you to a place of peace and prosperity that you never thought was possible to obtain. Amen, Dee! Amen!


rei October 7, 2015 at 5:13 am

He Eventually Proposed But Then Changed His Mind…i felt betrayed after all the promises and efforts that he’ve said and made.. what happened to all of those? I am also a Christian, but does get depressed also, i felt that i am lost with myself and my faith bec’ of the emotion that i’m feeling. though i know that our Lord God will help me through all this… but im feeling bad, i need wisdom i need faith. please pray for me.


thea October 7, 2015 at 7:49 am

Sometimes I feel so lonely and depressed, my husband divorced me few months back and now I am living with my 2 kids.
I just want to be happy again and be loved and cared for again.


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